hrp0089p2-p243 | Growth & Syndromes P2 | ESPE2018

Effect of Combined GH and Estrogen Treatment on the Lipid Profile and Systolic Function of the Left Ventricle in Girls with Turner Syndrome (TS)

Shiryaeva Tatiana , Nagaeva Elena , Pankratova Maria , Chikulaeva Olga , Volevodz Natalia , Peterkova Valentina

Background: The risk of cardiovascular diseases is increased in girls with TS. The influence by combined GH and estrogen treatment on a condition of cardiovascular system is actively discussed.Objective and hypotheses: We performed this study to assess th effects of combined GH and estrogen treatment on lipid metabolism and systolic function of the left ventricle (LV) in girls with Turner syndrome without clinically relevant cardiac abnormalities.<p ...

hrp0084p2-547 | Puberty | ESPE2015

The Impact of Growth Hormone (GH) Therapy Combined with Estrogens on Blood Pressure (BP), Cardiac Left Ventricular (LV) Dimensions and Lipid Metabolism in Pubertal Girls with Turner’s Syndrome (TS)

Nagaeva Elena , Shiryaeva Tatiana , Volevodz Natalia , Chikulaeva Olga , Pankratova Maria , Gavrilova Anna , Peterkova Valentina

Background: The risk of hypertension is estimated to occur in 7–17% of children and adolescents with TS. Even girls with TS who are normotensive have been shown an abnormal circadian BP rhythm, increasing the risk of end-organ hypertensive damage.Objective and hypotheses: We performed this study to assess the effects of GH treatment combined with estrogens for short stature on LV dimensions, systemic BP and lipid metabolism in girls with TS without ...